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Citation
SMITH J, GHEYAS A & BURT D (2016) Animal genomics and infectious disease resistance in poultry: -EN- -FR- La génomique animale et la résistance aux maladies infectieuses chez les volailles -ES- Genómica animal y resistencia a las enfermedades infecciosas en las aves de corral. Revue Scientifique et Technique de l'OIE, 35 (1), pp. 105-119. https://doi.org/10.20506/rst.35.1.2421
Abstract
Avian pathogens are responsible for major costs to society, both in terms of
huge economic losses to the poultry industry and their implications for human
health. The health and welfare of millions of birds is under continued threat from
many infectious diseases, some of which are increasing in virulence and thus
becoming harder to control, such as Marek’s disease virus and avian influenza
viruses. The current era in animal genomics has seen huge developments in both
technologies and resources, which means that researchers have never been in
a better position to investigate the genetics of disease resistance and determine
the underlying genes/mutations which make birds susceptible or resistant to
infection. Avian genomics has reached a point where the biological mechanisms
of infectious diseases can be investigated and understood in poultry and other
avian species. Knowledge of genes conferring disease resistance can be used in
selective breeding programmes or to develop vaccines which help to control the
effects of these pathogens, which have such a major impact on birds and humans
alike.
Keywords
Animal quantitative trait locus database; Avian; Avian influenza; Candidate gene; Chicken; Disease resistance; Genomics; Infection; Marek's disease virus; Poultry; Salmonella
Journal
Revue Scientifique et Technique de l'OIE: Volume 35, Issue 1
Status | Published |
---|---|
Funders | Biotechnology and Biological Sciences Research Council |
Publication date | 01/04/2016 |
Publication date online | 01/04/2016 |
Date accepted by journal | 18/01/2016 |
Publisher | O.I.E (World Organisation for Animal Health) |
ISSN | 0253-1933 |
eISSN | 1608-0637 |
People (1)
Lecturer in Aquaculture Production Scien, Institute of Aquaculture