The annual incidence of diabetic complications in a population of patients with Type 1 and Type 2 diabetes

Citation

McAlpine RR, Morris AD, Emslie-Smith AM, James P & Evans J (2005) The annual incidence of diabetic complications in a population of patients with Type 1 and Type 2 diabetes. Diabetic Medicine, 22 (3), pp. 348-352. https://doi.org/10.1111/j.1464-5491.2004.01391.x

Abstract
Aim: The DARTS diabetes register was used to determine incidence rates of diabetes and related complications in 1997. Methods: The diabetes register records detailed clinical information for all patients diagnosed with diabetes in Tayside, Scotland. The study population included patients who were alive and registered with a Tayside GP for the duration of 1997 or who died in Tayside during this time. Patients who had diabetes prior to 1997, those who developed diabetes in 1997, and those who developed diabetic complications in 1997, were identified. Results: In the Tayside population of 385 774 at the start of 1997, there were 942 and 6632 patients with Type 1 and Type 2 diabetes, with a further 29 and 744 patients diagnosed in 1997. The incidence rates (with 95% confidence intervals) of diabetic complications per 1000 patients with Type 1 and Type 2 diabetes, respectively, were: angina 8.8 (4.5-17.3) and 38.4 (33.4-44.2); myocardial infarction 8.6 (4.4-16.9) and 21.9 (18.4-25.9); cerebrovascular accident 1.1 (0.3-6.0) and 14.2 (11.6-17.5); lower extremity amputation 3.2 (1.2-9.4) and 3.1 (2.1-4.8); peripheral vascular disease 5.5 (2.4-12.8) and 13.6 (11.0-16.8); registered blindness 1.1 (0.3-5.9) and 1.6 (0.9-2.9); end-stage renal failure 6.4 (3.0-13.8) and 5.0 (3.6-7.0). Mortality was 14.6 per 1000 (9.6-25.7) in Type 1 diabetes and 50.0 per 1000 (45.1-55.3) in Type 2 diabetes. Conclusion: This study provides baseline figures for rates of diabetic complications for Type 1 and Type 2 diabetes, and confirms the increased burden of macrovascular disease in Type 2 diabetes.

Keywords
Diabetes mellitus; Diabetic complications; Incidence; Macrovascular; Microvascular

Journal
Diabetic Medicine: Volume 22, Issue 3