Long-term course of cognitive impairment in schizophrenia

Citation

Morrison G, O'Carroll R & McCreadie R (2006) Long-term course of cognitive impairment in schizophrenia. British Journal of Psychiatry, 189 (6), pp. 556-557. https://doi.org/10.1192/bjp.bp.105.016113

Abstract
The aim of this study was to examine the long-term course of cognitive impairment in people with schizophrenia. Forty-three people with schizophrenia were followed up over an average of 33 years along with a control group of 12 matched individuals free from psychosis. Cognitive function was assessed at baseline and follow-up. The participants with schizophrenia were found to show impairment in verbal and non-verbal intelligence at baseline compared with estimated premorbid scores, this was not found in the control group. At follow-up there was a significant decline in non-verbal intelligence over time in participants with schizophrenia compared with controls (P=0.007). This differential change over time was not seen in verbal intelligence (P= 0.318).

Journal
British Journal of Psychiatry: Volume 189, Issue 6