Two distinct STLV-1 subtypes infecting Mandrillus sphinx follow the geographic distribution of their hosts

Citation

Makuwa M, Souquiere S, Clifford SL, Telfer PT, Salle B, Bourry O, Onanga R, Mouinga-Ondeme A, Wickings EJ, Abernethy K, Rouquet P, Simon F & Roques P (2004) Two distinct STLV-1 subtypes infecting Mandrillus sphinx follow the geographic distribution of their hosts. AIDS Research and Human Retroviruses, 20 (10), pp. 1137-1143. https://doi.org/10.1089/aid.2004.20.1137

Abstract
The mandrill (Mandrillus sphinx) has been shown to be infected with an STLV-1 closely related to HTLV-1. Two distinct STLV-1 subtypes (D and F) infect wild mandrills with high overall prevalence (27.0%) but are different with respect to their phylogenetic relationship and parallel to the mandrills' geographic range. The clustering of these new STLV-1mnd sequences with HTLV-1 subtype D and F suggests first, past simian-tohuman transmissions in Central Africa and second, that species barriers are easier to cross over than geographic barriers.

Journal
AIDS Research and Human Retroviruses: Volume 20, Issue 10

People

Professor Katharine Abernethy

Professor, Biological and Environmental Sciences