Senior Animal Care Technician (FNS)
University of Stirling Marine Environmental Research Laboratory, Machrihanish
I'm based at the Institute of Aquaculture's marine lab at Machrihanish in Kintyre. We're developing new products and methods, primarily for the salmon aquaculture industry. I'm the GLP Study Director covering all of our aquatic work on veterinary medicines and vaccines, feeds, chemicals, eco-toxicology, product support and genetics. My prior work has been in the field of developmental genetics, using zebrafish embryos to study inherited brain and muscle diseases and develop models for drug identification.
A zebrafish model of Duchenne Muscular Dystrophy. 3rd European Conference on Zebrafish and Medaka Development and Genetics
Comparative study of the susceptibility of triploid and diploid Atlantic salmon to infection with the sea louse (Lepeophtheirus salmonis).. 9th International Sea Lice Conference
Norwegian Institute of Marine Research
http://www.imr.no/sealice2012/en
Use of RAD sequencing to isolate a sex-specific SNP marker in the salmon
louse Lepeophtheirus salmonis. 10th International Sea Lice Conference
http://sealice2014.businesscatalyst.com/…-v6.2-final2.pdf
Sequential treatment of Atlantic salmon (Salmo salar) with SLICE®
(emamectin benzoate) and hydrogen peroxide for the control of salmon lice. 10th International Sea Lice Conference
http://sealice2014.businesscatalyst.com/…-v6.2-final2.pdf
Recombinant vaccine efficacy trials against infectious larval salmon lice
stages following intraperitoneal immunisation of Atlantic salmon with 9
vaccine candidates. 10th International Sea Lice Conference
http://sealice2014.businesscatalyst.com/…-v6.2-final2.pdf
Drug susceptibility assessment of sea lice by time-to-response toxicity analysis. 10th International Sea Lice Conference
http://sealice2014.businesscatalyst.com/…-v6.2-final2.pdf
A Novel In Vitro Method for Testing Compounds on Sea Lice. 10th International Sea Lice Conference
http://sealice2014.businesscatalyst.com/…-v6.2-final2.pdf
Presentation on salmon aquaculture and demonstration. Seafood in Schools, Campbeltown Grammar School
Seafood Scotland
Exhibition over two mornings for local primary school children. Joint with Marine Scotland, Kintyre Smokehouse, RNLI, Campbeltown Grammar School. We gave presentations and taught children about salmon and sea lice.
Member of an Ad-Hoc Expert Group (AHEG) reporting to the CVMP on approval of veterinary medicines in Europe via the European Medicines Agency.
Member of the Research Quality Association (MRQA)
Member of the Royal Society of Biology (MRSB)
Marine Environment Research Laboratory
At Machrihanish we carry out contract research to GLP for the aquaculture, animal feed and veterinary pharma sectors, as well as hosting academic research and students from around the world. The team identify and evaluate potential tools for control of salmon pathogens and parasites using in-house challenge models, test improved feeds, and find bespoke solutions to pressing industry problems. My role is to design protocols, direct and carry out studies, collect and analyse data and report on what we find for customers. Also interested in environment, early development, evolution.
Article
Tschesche C, Bekaert M, Bassett DI, Boyd S, Bron JE & Sturm A (2022) Key role of mitochondrial mutation Leu107Ser (COX1) in deltamethrin resistance in salmon lice (Lepeophtheirus salmonis). Scientific Reports, 12 (1), Art. No.: 10356. https://doi.org/10.1038/s41598-022-14023-1
Article
Tschesche C, Bekaert M, Bassett DI, Mitchell C, North B, Boyd S, Carmona‐Antoñanzas G, Bron JE & Sturm A (2021) Investigation of deltamethrin resistance in salmon lice (Lepeophtheirus salmonis) provides no evidence for roles of mutations in voltage-gated sodium channels. Pest Management Science, 77 (2), pp. 1052-1060. https://doi.org/10.1002/ps.6120
Article
Humble JL, Carmona-Antoñanzas G, McNair CM, Nelson DR, Bassett DI, Egholm I, Bron JE, Bekaert M & Sturm A (2019) Genome-wide survey of cytochrome P450 genes in the salmon louse Lepeophtheirus salmonis (Krøyer, 1837). Parasites and Vectors, 12 (1), Art. No.: 563. https://doi.org/10.1186/s13071-019-3808-x
Article
Carmona-Antoñanzas G, Helgesen KO, Humble JL, Tschesche C, Bakke MJ, Gamble L, Bekaert M, Bassett DI, Horsberg TE, Bron JE & Sturm A (2019) Mutations in voltage-gated sodium channels from pyrethroid resistant salmon lice (Lepeophtheirus salmonis). Pest Management Science, 75 (2), pp. 527-536. https://doi.org/10.1002/ps.5151
Article
Carmona-Antoñanzas G, Bekaert M, Humble JL, Boyd S, Roy W, Bassett DI, Houston RD, Gharbi K, Bron JE & Sturm A (2017) Maternal inheritance of deltamethrin resistance in the salmon louse Lepeophtheirus salmonis (Krøyer) is associated with unique mtDNA haplotypes. PLoS ONE, 12 (7), Art. No.: e0180625. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0180625; https://doi.org/10.1371/journal.pone.0180625
Conference Paper (unpublished)
Bioassays and contract research at the Machrihanish Environment Research Laboratories
Bassett DI & Preston AC (2017) Bioassays and contract research at the Machrihanish Environment Research Laboratories. MEDFRI workshop on non-medicinal approaches to sea lice, Trondheim, Norway, 26.01.2017-27.01.2017.
Article
Time-to-response toxicity analysis as a method for drug susceptibility assessment in salmon lice
Carmona-Antoñanzas G, Humble JL, Carmichael SN, Heumann J, Christie HRL, Green DM, Bassett DI, Bron JE & Sturm A (2016) Time-to-response toxicity analysis as a method for drug susceptibility assessment in salmon lice. Aquaculture, 464, pp. 570-575. https://doi.org/10.1016/j.aquaculture.2016.08.007
Poster
A Novel In Vitro Method for Testing Compounds on Sea Lice
Bassett DI, Preston AC, Perret J, Barnett S & Roy W (2015) A Novel In Vitro Method for Testing Compounds on Sea Lice. 10th International Sea Lice Conference, Portland, ME, USA, 31.08.2014-05.09.2014. http://sealice2014.businesscatalyst.com/assets/abstract-book-v6.2-final2.pdf
Presentation / Talk
Monaghan S, McNair C, McDonald HC, Ireland J, Hamilton S, Knox D, Roy W, Thompson K, Adams A, Richards R, Smith P, Bassett DI, Matthew C, Preston AC, Groves F, Boyd S, Kanellos T, Asper D & Bron J (2015) Recombinant vaccine efficacy trials against infectious larval salmon lice stages following intraperitoneal immunisation of Atlantic salmon with 9 vaccine candidates. 10th International Sea Lice Conference, Portland, ME, USA, 31.08.2014-05.09.2014. http://sealice2014.businesscatalyst.com/assets/abstract-book-v6.2-final2.pdf
Presentation / Talk
Morris D, Gould C, Roy W, Bassett DI & Cockerill D (2014) Sequential treatment of Atlantic salmon (Salmo salar) with SLICE® (emamectin benzoate) and hydrogen peroxide for the control of salmon lice (Lepeophtheirus salmonis). 10th International Sea Lice Conference, Portland, ME, USA, 31.08.2014-05.09.2014. http://sealice2014.businesscatalyst.com/assets/abstract-book-v6.2-final2.pdf
Conference Paper (published)
Carmichael SN, Bekaert M, Taggart J, Ireland J, Christie HRL, Bassett DI, Bron J, Skuce P, Gharbi K & Skern-Mauritzen R (2014) Use of RAD sequencing to isolate a sex-specific SNP marker in the salmonlouse Lepeophtheirus salmonis (Kroyer, 1837). In: Sea Lice 2014: The 10th International Sea Lice Conference Book of Abstracts. 10th International Sea Lice Conference, Portland, ME, USA, 31.08.2014-05.09.2014. Portland, ME, USA: Fish Vet Group, p. 54. http://sealice2014.businesscatalyst.com/assets/abstract-book-v6.2-final2.pdf
Poster
Drug susceptibility assessment of sea lice by time-to-response toxicity analysis
Carmichael SN, Christie HRL, Heumann J, Bassett DI, Bron J & Sturm A (2014) Drug susceptibility assessment of sea lice by time-to-response toxicity analysis. 10th International Sea Lice Conference, Portland, ME, USA, 31.08.2014-05.09.2014. http://sealice2014.businesscatalyst.com/assets/abstract-book-v6.2-final2.pdf
Article
Carmichael SN, Bekaert M, Taggart J, Christie HRL, Bassett DI, Bron J, Skuce P, Gharbi K, Skern-Mauritzen R & Sturm A (2013) Identification of a sex-linked SNP marker in the salmon louse (Lepeophtheirus salmonis) using RAD sequencing. PLoS ONE, 8 (10), Art. No.: e77832. https://doi.org/10.1371/journal.pone.0077832
Research Report
Tildesley A, Boyd S, Matthew C, Barnett S, Bassett DI, Cowan M & Roy W (2012) Evaluation Of Sensitivity To Chemotherapeutants In Successive Generations Of Lepeoptheirus Salmonis From A Resistant Population. Scottish Aquaculture Research Forum Report 069 (Editor) Scottish Aquaculture Research Forum. Scottish Aquaculture Research Forum Reports, 069. Scottish Aquaculture Research Forum. http://www.sarf.org.uk/cms-assets/documents/72452-592533.sarf069.pdf
Article
Thornhill P, Bassett DI, Lochmuller H, Bushby K & Straub V (2008) Developmental defects in a zebrafish model for muscular dystrophies associated with the loss of fukutin-related protein (FKRP). Brain, 131 (6), pp. 1551-1561. http://brain.oxfordjournals.org/content/131/6/1551.long; https://doi.org/10.1093/brain/awn078
Article
Identification of a zebrafish model of muscular dystrophy
Bassett DI & Currie PD (2004) Identification of a zebrafish model of muscular dystrophy. Clinical and Experimental Pharmacology and Physiology, 31 (8), pp. 537-540. http://onlinelibrary.wiley.com/doi/10.1111/j.1440-1681.2004.04030.x/abstract; https://doi.org/10.1111/j.1440-1681.2004.04030.x
Article
Dystrophin is required for the formation of stable muscle attachments in the zebrafish embryo
Bassett DI, Bryson-Richardson RJ, Daggett DF, Gautier P, Keenan DG & Currie PD (2003) Dystrophin is required for the formation of stable muscle attachments in the zebrafish embryo. Development, 130 (23), pp. 5851-5860. http://www.ncbi.nlm.nih.gov/pubmed/14573513; https://doi.org/10.1242/dev.00799
Article
The zebrafish as a model for muscular dystrophy and congenital myopathy
Bassett DI & Currie PD (2003) The zebrafish as a model for muscular dystrophy and congenital myopathy. Human Molecular Genetics, 12 (Supplement 2), pp. R265-R270. https://doi.org/10.1093/hmg/ddg279
Article
Bassett DI (2003) Identification and developmental expression of a macrophage stimulating 1/hepatocyte growth factor-like 1 orthologue in the zebrafish. Development Genes and Evolution, 213 (7), pp. 360-362. https://doi.org/10.1007/s00427-003-0339-3
Conference Paper (unpublished)
A zebrafish model of Duchenne muscular Dystrophy
Bassett DI, Bryson-Richardson RJ, Daggett DF, Gautier P, Keenan DG & Currie PD (2003) A zebrafish model of Duchenne muscular Dystrophy. 3rd European Conference on Zebrafish and Medaka Development and Genetics, Paris, 11.06.2003-14.06.2003.
Article
Bassett DI (2001) Fish are Rising. Genome Biology, 2 (7), Art. No.: 4016. https://doi.org/10.1186/gb-2001-2-7-reports4016
I host Stirling MSc classes as a stop on the tour every year, as well as classes from SAMS. We also host local schools, and take part in Seafood in Schools including at the Royal Highland Show.
